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Full-spectrum ashwagandha root extract

KSM-66® Ashwagandha

The root-only, full-spectrum ashwagandha extract.

Brand / technology by Ixoreal Biomed

KSM-66® is the ashwagandha root extract in our capsules. Research on this ingredient includes studies of stress and sleep. We chose a root-only extract with a consistent 5% withanolide concentration.

Why this matters

A researched ashwagandha root extract in two daily capsules.

Made from the root

KSM-66® uses ashwagandha root, with no leaf extract. It is standardised to 5% withanolides, naturally occurring plant compounds.

What the research looks at

One placebo-controlled study followed 64 adults with a history of chronic stress for 60 days, measuring perceived stress and cortisol. The studies below explain the findings for this extract; they did not test our finished capsules.

How it fits into your day

Two capsules provide 600 mg KSM-66®, including 30 mg withanolides.

Explore the evidence and details

The technology

KSM-66® is standardised to ≥5 % withanolides (measured by HPLC) and is produced with a proprietary “Green Chemistry” extraction — water-based, with no alcohol or chemical solvents. “Full-spectrum” means it aims to keep the natural balance of the root’s constituents rather than concentrating a single fraction.

A large clinical program

KSM-66® has been used in multiple randomised, double-blind, placebo-controlled human trials. The sources below describe the participants, duration and measurements.

Published research

Selected peer-reviewed human trials that used KSM-66® specifically:

  • Chandrasekhar et al. (2012)

    Randomised, double-blind, placebo-controlled trial (n=64) in adults with a history of chronic stress; investigated perceived-stress scales and serum cortisol over 60 days.

    Indian Journal of Psychological MedicinePubMed/MEDLINE, RCT

    PubMed
  • Salve et al. (2019)

    Randomised, double-blind, placebo-controlled trial (n=60 healthy adults), three arms over 8 weeks; investigated stress scales, serum cortisol and a sleep-quality measure.

    CureusPubMed

    PubMed
  • Wankhede et al. (2015)

    Randomised, double-blind, placebo-controlled trial (n=57 men) alongside an 8-week resistance-training program; investigated muscle strength, body composition and recovery markers.

    Journal of the International Society of Sports NutritionPubMed/MEDLINE, RCT

    PubMed

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