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Full-spectrum ashwagandha root extract

KSM-66® Ashwagandha

The root-only, full-spectrum ashwagandha extract.

Supplied by Ixoreal Biomed

KSM-66® is a full-spectrum ashwagandha (Withania somnifera) extract from Ixoreal Biomed, made from the root only — no leaves.

The technology

KSM-66® is standardised to ≥5% withanolides (measured by HPLC) and is produced with a proprietary “Green Chemistry” extraction — water-based, with no alcohol or chemical solvents. “Full-spectrum” means it aims to keep the natural balance of the root’s constituents rather than concentrating a single fraction.

A large clinical program

KSM-66® is one of the most extensively studied ashwagandha extracts, with a substantial program of randomised, double-blind, placebo-controlled human trials. A selection is listed below and described neutrally — what was investigated, not what the product does for you.

Published research

Selected peer-reviewed human trials that used KSM-66® specifically:

  • Chandrasekhar et al. (2012)

    Randomised, double-blind, placebo-controlled trial (n=64) in adults with a history of chronic stress; investigated perceived-stress scales and serum cortisol over 60 days.

    Indian Journal of Psychological MedicinePubMed/MEDLINE · RCT

    PubMed ↗
  • Salve et al. (2019)

    Randomised, double-blind, placebo-controlled trial (n=60 healthy adults), three arms over 8 weeks; investigated stress scales, serum cortisol and a sleep-quality measure.

    CureusPubMed

    PubMed ↗
  • Wankhede et al. (2015)

    Randomised, double-blind, placebo-controlled trial (n=57 men) alongside an 8-week resistance-training program; investigated muscle strength, body composition and recovery markers.

    Journal of the International Society of Sports NutritionPubMed/MEDLINE · RCT

    PubMed ↗
Powers this product

A note on claimsEU health claims for botanicals such as ashwagandha are “on hold”, so there is no authorised claim — this page describes the extract and the published research neutrally, never as a product benefit.